fac-[Re(CO)3(L6)(H2O)][NO3]

CAS: F: C24H14N5O7ReS W: 702.67

fac- (compound 6), the rhenium(I) tricarbonyl aqua complex, is an anticancer agent associated with mitochondrial dysfunc

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Bioactivity	fac-[Re(CO)3(L6)(H2O)][NO3] (compound 6), the rhenium(I) tricarbonyl aqua complex, is an anticancer agent associated with mitochondrial dysfunction. fac-[Re(CO)3(L6)(H2O)][NO3] is cytotoxic to prostate cancer cells, IC50=50 nM (PC-3 cells). fac-[Re(CO)3(L6)(H2O)][NO3] mainly accumulates in the nucleus, down-regulates ATP production in PC3 cells, and promotes apoptosis. However, fac-[Re(CO)3(L6)(H2O)][NO3] did not induce necrosis, pyrodeath and autophagy[1].
In Vivo	fac-[Re(CO)3(L6)(H2O)][NO3]
Name	fac-[Re(CO)3(L6)(H2O)][NO3]
Formula	C24H14N5O7ReS
Molar Mass	702.67
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Enslin LE, et al. Rhenium(I) Tricarbonyl Complexes of 1,10-Phenanthroline Derivatives with Unexpectedly High Cytotoxicity. Inorg Chem. 2023 Aug 7;62(31):12237-12251.

22-(4′-py)-JA